I thought it was me. She thought it was her. Turns out it was my diabetes. Prime Male Medical assured their medication would work and they were right, or it ...
The most common side effects of Tadalafil: headache; flushing; upset stomach; abnormal vision, such as changes in color vision (such as having a blue color tinge) and blurred vision; stuffy or runny nose; back pain; muscle pain; nausea; dizziness; rash. .
The bark of the African evergreen yohimbe tree contains a compound called yohimbine, which has been traditionally used as an aphrodisiac.
When evaluating a patient with suspected ED, a thorough physical examination is warranted to exclude prostate and penile abnormalities that might contribute to the condition. A complete sexual history that includes the frequency, quality, and duration of erections and presence of morning erections is essential in the classification of ED. Obtaining a medical history allows the health care provider to rule out conditions, such as hypogonadism, that may be causing ED. On the other hand, ED is often the presenting symptom for unidentified cardiovascular disease.
Another second-line therapy is the use of alprostadil, either intracavernosal or intraurethral. Two products are available for direct injection, Caverject (Pfizer) or Edex (Actient). A small needle is used to inject the medication into the lateral aspect of the penis through a small-gauge needle.
Erectile Dysfunction (or impotence) is the inability to get or keep an erection long enough to have sex. It’s very common in men, especially as you get older. According to research from the Irish Heart Foundation, almost 20% of men in their 50s suffer from ED, climbing to 38% of men in their 60s, and 57% of men over 70.
The needle must never touch any object other than the alcohol-wiped ampule stopper or penile skin. If the needle is contaminated, throw out the syringe and start over. Trimix Side Effects
Erectile dysfunction (ED) is the inability to get or maintain an erection hard enough for satisfactory sex. The causes of ED can be psychological or physical and usually result in reduced blood flow to the penis - making it harder to get an erection.
Continuing Professional Development (CPD) Education Committee E-Learning Revalidation
A meta-analysis of 36 744 men with ED in 12 prospective cohort studies found that the presence of ED significantly increased the risk of CVD, CAD, stroke and all-cause mortality, and the presence of ED was an independent risk factor for CVD. Ponholzer et al found that men with moderate to severe ED had a 65% increased relative risk for developing symptomatic CAD compared with men who did not have ED.26
endothelin receptor antagonists – such as bosentan, ambrisentan and macitentansoluble guanylate cyclase stimulators – such as riociguatprostaglandins – such as epoprostenol, iloprost and treprostinilcalcium channel blockers – nifedipine, diltiazem, nicardipine and amlodipine
Likewise, a disease called atherosclerosis can cause erectile dysfunction by restricting blood flow to the penis.
In recent years, there has been more and more research pertaining to the rise of pornography-related sexual dysfunction. Researchers believe that the unique properties of internet pornography, including its easy accessibility, limitlessness, variety and format, may be conditioning younger men’s sexual arousal to aspects of sexuality that do not easily transition to their real-life partners. It’s possible that for men who are constantly exposed to internet pornography, sexual activity with their real-life partners often doesn’t meet their expectations, which can lead to arousal declines.
The PDE5 inhibitors are commonly prescribed for the management of ED. As their name indicates, these agents work to block the type-5–mediated catabolism of cGMP, allowing NO-induced vasodilatation of the penile vasculature. Sildenafil was the first PDE5 inhibitor to arrive on the market, in 1998. The usual dose of sildenafil is 50 mg (25 to 100 mg) taken one hour before sexual activity. The effects of sildenafil last for approximately four hours, and patients should be instructed to use no more than one dose within 24 hours. Fatty meals reduce the absorption of sildenafil; therefore, the drug should be taken on an empty stomach.5,11 Vardenafil (Levitra), the first second-generation PDE5 inhibitor to be developed, is given at a usual dose of 10 mg (2.5 to 20 mg) one hour before sexual activity. Elderly patients and those with moderate liver dysfunction should receive a lower initial dose of 5 mg. Vardenafil begins working within 30 to 45 minutes after administration and lasts for about four hours. As with sildenafil, patients taking vardenafil should not use more than one dose within a 24-hour period. Patients should not take vardenafil within three hours of fatty meals, due to a reduction in absorption.5,12 The newest PDE5 inhibitor is tadalafil (Cialis), which has a longer duration of action--approximately 36 hours--than sildenafil or vardenafil. In addition, the usual dose of 10 mg (5 to 20 mg) should be taken about 30 minutes before sexual activity--possibly allowing patients more opportunity for spontaneity. Food intake does not appear to affect the absorption of tadalafil; thus, the drug may be taken without regard to meals.5,13 Though considered generally safe for most patients, including those taking multiple antihypertensives, PDE5 inhibitors are not a viable treatment option for every man with ED. Patients with a cardiovascular history that includes a recent myocardial infarction or stroke (within the past two weeks), cerebral vascular accident, life-threatening arrhythmia, hypertension (blood pressure >170/100 mmHg), hypotension (blood pressure <90/50 mmHg), unstable angina, and/or moderate to severe heart failure (New York Heart Association class IIIor IV) should not receive therapy with these agents. The risks and benefits associated with PDE5 inhibitor therapy and the patient's medical history must be assessed. 5,6,11-13
If you think you have ED, a good first step is to talk with your doctor. The treatment you need will depend on what’s causing it.
There are also injectable drugs for erectile dysfunction. Some men sustain stronger erections by injecting these medications directly into the penis. These drugs work by widening the blood vessels, causing the penis to become engorged with blood. Another option is a medicated pellet that is inserted into the urethra and can trigger an erection within 10 minutes. Patients should discuss the use of these injections in detail with their doctor before use.